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KMID : 0665220100230010063
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Korean Journal of Food and Nutrition
2010 Volume.23 No. 1 p.63 ~ p.69
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Screening and Optimal Culture Conditions of Antibiotic-Producing Actinomycetes B-51 for Multidrug Resistant Acinetobacter baumannii
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Rhee Moon-Soo
Kim Gwan-Pil
Bang Byung-Ho
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Abstract
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With the increase of the use of antibiotics and invasive procedures, infections caused by multidrug-resistant Acinetobacter baumannii(MRAB) are increasing. We screened the antibiotic producing strain B-51 for antibacterial activity against MRAB from the soils and studied the effects of culture medium on the antibiotic production of B-51. The medium conditions for maximum antibiotic productivity of B-51 was 2% glycerol, 0.5% soybean meal, 0.01% , 0.01% and 0.01% at an initial pH of 6.0, at for 76 h.
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KEYWORD
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Acinetobacter baumannii, Actinomycetes, antibiotic, cultural conditions, MRAB
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